The region's first controlled-access highway, the Sixth Avenue Freeway, came into being during World War II. The initial segment of the Valley Highway (later incorporated into Interstate 25) opened in 1951.

Denver's earliest malls were not built directly adjacent to these initial stretches of expressway, although UNIVERSITY HILLS CENTER (1951-1956) -in the south of the city / county- was mighty close to a portion of I-25 that was open by 1960.

Technically, Denver's BEAR VALLEY CENTER (1966) was the first "freeway friendly" shopping mall in / around The Mile-High City. This was quickly followed by Adams County's NORTH VALLEY CENTER (1967), Englewood's CINDERELLA CITY and Adams County's NORTHGLENN, all of which were open by 1968.

The RTD Light Rail system was built to serve Denver and its environs. The first trains on the initial 5.3 route mile D Line were put into operation on October 7, 1994. Expansions opened in July 2000, April 2002, November 2006, April 2013, April  2016, February 2017 and May 2019. RTD Light Rail now extends for 60.1 route miles and serves fifty-seven stations, including stops at CITYCENTER ENGLEWOOD (a redevelopment of CINDERELLA CITY) and PARK MEADOWS MALL. 

The RTD Commuter Rail network was inaugurated, with service on the 23.5 route mile A Line, on April 22, 2016. The electric and diesel network was extended in July 2016, April 2019 and September 2020. It currently extends for 54 route miles and serves twenty-seven stations, including a stop at DOWNTOWN WESTMINSTER (a redevelopment of WESTMINSTER MALL).