The south anchor box housed department stores operated by Meyers-Arnold (1968-1987) and Uptons (1987-1999). It morphed into the Greenville Technical College ARC (Admissions & Registration Center), which serves as a one-stop student orientation facility and bookstore.
Photo from http://www.gvltec.edu (Greenville Technical College)
University Center of Greenville is part of today's multi-college satellite campus, which inhabits the old McALISTER SQUARE mall.
Graphic from https://greenville.org (University Center Greenville)